What goes up, must come down. Occasionally more quickly and in more (flaming) pieces than originally intended.

For anyone who's not up on what Antares is, it's an uncrewed vehicle and NASA is reporting that although there was property damage no one on the ground was hurt.

http://www.slate.com/blogs/bad_astronomy/2014/10/28/breaking_antares_rocket_explodes_on_takeoff.html

https://www.youtube.com/watch?v=aL5eddt-iAo